Advances in the studies on the anti-tumor effect and mechanism of baicalein

Abstract

Abstract: Baicalein is applidied in clinic as Qing Re traditional Chinese herb.The recent research indicate that baicalein in scutellaria has anti-tumor effect by regulating arachidonic acid (AA)metabolites, inducing cancer cell cycle arrest and apoptosis, restraining tumor new angiogenesis, inhibiting cancer cell invasion and aversion, and enhancing cancer cell sensitiveness to chemotherapeutics.This article reviews the development of its anti-tumor effect and mechanism and provides theoretical evidence for clinical application.

Key words: Baicalein, anti-tumor, mechanism

CLC Number:

R931.71

MAO Jie, XU Shan-shui, SHEN Li-li, WANG Xuan-zhi. Advances in the studies on the anti-tumor effect and mechanism of baicalein[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2009, 14(10): 1178-1182.

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