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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2014, Vol. 19 ›› Issue (3): 334-340.

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Cell Metabonomics and its Applications

YAO Wei-feng1,2,3, ZHOU Li-na1,3, ZHANG Li1,3, DING An-wei1,3, LI Wei1   

  1. 1Nanjing University of Chinese Medicine,Nanjing 210023, Jiangsu, China;
    2Engineering Laboratory of Jiangsu Province for Antitumor Empirical Formula Research and Industrialization, Nanjing 210023, Jiangsu, China;
    3Jiangsu Key Laboratory for High Technology of TCM Formulae,Nanjing 210023, Jiangsu, China
  • Received:2013-04-20 Revised:2014-02-25 Online:2014-03-26 Published:2014-04-10

Abstract: Cell metabonomics is often defined as the set of small molecule metabolites in intracellular and membrane. Metabolites are involved in a diverse range of intracellular processes, and their concentrations closely reflect the phenotype of an organism, tissue, or cell. Cell metabonomics is an emerging filed, and it can solve fundamental biological questions and is used to observe metabolic phenomena in cells. In the postgenomics era, cell metabonomics has many potential advantages compared with currently used methods, and it has become a promising analytical tools. This paper briefly reviewed the major research process of cell metabonomics and the progress in application and the integration with other omics.

Key words: cell metabonomics, research process, integration with other omics

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