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Table of Content

    10 June 2020, Volume 28 Issue 6
    Progress on the understanding the involvement of exercise in epigenetic regulation of early childhood development
    ZHANG Ting
    2020, 28(6):  605-608.  DOI: 10.11852/zgetbjzz2020-0876
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    During early childhood development,the dynamic programming of epigenetics is closely correlated with the dietary balance of infants and young children,but also closely related to children′s physical movement.Diet and physical movement jointly affect the upstream metabolic balance of epigenetic modification,which fully reflects the interaction between genetics and the internal environment during the development of children.To this end,this article introduces the effect of physical activities on the body′s epigenetic modification and even the regulation of downstream functional genes,with emphasis on the progress on epigenetics mechanism from three different levels:the participation of movement in DNA methylation,chromosomal histone modification and miRNA regulation,thereby providing a more systematic epigenetic basis for physical movement′s needs in early childhood development,especially for parent-child exercise in early childhood development.
    Investigation and analysis on the status of outdoor activities of preschool children in Shanghai
    LIU Mei-yan, WU Dan, HUO Yan-yan, WANG Xiu-lian, GUO Qian-wen, SUN Fan-fan, JIANG Lian, SHI Hui-jie, CHEN Jin-jin
    2020, 28(6):  609-612.  DOI: 10.11852/zgetbjzz2019-0743
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    Objective To understand the participation status of physical activity of preschool children in Shanghai through a cross-sectional survey . Methods A self-designed questionnaire on children′s outdoor activity were used from March to June in 2018 to investigate the daily activities of 454 preschoolers.T test was used to compare the mean of the two groups of normal distribution data,non-normal date are tested by non-parametric test,and Chi-square test was used to compare the rate. Results The average time for participating in outdoor activities of preschool children was 1.49 hours/day on workday,and it was 2.64 hours/day on weekend.The top five most popular sports for children were walking,skateboarding/skating,running,cycling and dance,which mainly were family-based.There were statistically significant differences on preschool children′s sport types in different age groups and different degree of parental encouragement(P<0.05). Conclusion The status of outdoor activities for preschool children in Shanghai is not optimistic.It reflects the characteristics of the living environment of preschool children in Shanghai in terms of sports style,venues,accompanying people and sport event.
    Relationship of handgrip strength and body composition among school-age children
    LIU Jun-ting, HOU Dong-qing, ZHU Zhong-xin, GAO Ai-yu, YU Zhao-cang, LIN Ning-xiang, HUANG Gui-min, MI Jie
    2020, 28(6):  613-617.  DOI: 10.11852/zgetbjzz2019-0558
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    Objective To study the correlation between body composition and grip strength of school-age children and adolescents,in order to provide evidence for maintaining appropriate body composition when giving interventions to school-age obese children. Methods A questionnaire survey (lifestyle,dietary and exercise),bioelectrical impedance analysis of body composition and dominant hand grip strength tests were conducted among 15 118 school-age children aged 6-16 years in Beijing in 2018.Partial correlation,and multiple linear regression were used to analyze the correlation of body composition indicators and handgrip strength. Results The level of grip strength of children and adolescents in Beijing gradually increased with age.Grip strength of the normal weight group in boys increased from (9.7±2.6)kg in 6-8 years age group to (40.0±7.1)kg in 15-16 years age group,and grip strength of the normal weight group in girls increased from (8.9±2.6)kg in 6~8 years age group to (25.0±4.4)kg in 15-16 years age group,which was consistent with the change trend of skeletal muscle index of the upper limbs,and handgrip strength of boys was higher than that of girls.Adjusted for some related factors,the higher the fat free mass index(boys:r=0.597,girls:r=0.424)and the skeletal muscle index(boys:r=0.258,girls,r=0.102) were,the higher grip strength was(P<0.05). Conclusion Grip strength can reflect the trend of skeletal muscle.Reducing fat mass and increasing fat free mass can improve the grip strength.
    Association between anthropometric measurements and high blood pressure among Chinese children and adolescents aged 12-17 years
    ZHANG Hua-qin, MA Yun, SHEN Li, TAN Qiu-ping
    2020, 28(6):  618-622.  DOI: 10.11852/zgetbjzz2019-1017
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    Objective To analyze the prevalence of systolic blood pressure,diastolic blood pressure and high blood pressure in Chinese adolescents aged 12-17 years,and to explore the relationship between anthropometric measurements(BMI,waist circumference,waist-to-hip ratio,waist-to-height ratio) and high blood pressure,so as to provide reference for relevant departments to develop strategies for prevention and control of hypertension in children and adolescents. Methods Totally 5 554 children and adolescents aged 12-17 years with completed variables from “China Health and Nutrition Survey” conducted from 1991 to 2015 were selected as study subjects.The definition of high blood pressure was based on the national standard of “high blood pressure screening threshold for children and adolescents aged 7-18 years” issued by the National Health and Health Commission in 2018.Multivariate Logistic regression was used to analyze the association between high blood pressure and the four physical measures. Results From 1991 to 2015,the prevalence rates of high blood pressure isolated high systolic blood pressure,and isolated high diastolic blood pressure in children and adolescents aged 12-17 years in China were 9.67%,1.57%,and 6.41%,respectively.The high blood pressure prevalence rates of lean and normal,overweight and obesity group were 8.79%,17.88% and 27.45%,respectively. Meanwhile,the prevalence of isolated high systolic blood pressure were 1.39%,3.03% and 5.88%,respectively and the prevalence of isolated high diastolic pressure were 5.99%,10.91% and 12.75%,respectively.Multivariable Logistic regression model revealed that the risk of high blood pressure,isolated high systolic blood pressure and isolated high diastolic blood pressure increased with the elevation of BMI level(P<0.05). Conclusion The prevalence of high blood pressure in overweight and obese people aged 12-17 years in China is higher.Preventing and controlling the overweight and obesity is an important measure to cope with the high blood pressure of children and adolescents.
    Effect of birth weight on the growth of children under 7 years old
    WU Hua-hong, LI Hui, ZHANG Ya-qin, ZONG Xin-nan
    2020, 28(6):  623-626.  DOI: 10.11852/zgetbjzz2019-1112
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    Objective To investigate the effect of birth weight(BW) on the growth of children under 7 years old,and to explore the effect of intrauterine growth on physical growth in childhond. Methods A cross-sectional study was conducted in nine cities of Beijing,Harbin,Xi′an,Wuhan,Nanjing,Shanghai,Guangzhou,Fuzhou and Kunming from June to October in 2005.A stratified cluster sampling method was used to select 50 076 healthy children in urban areas.The subjects were divided into four groups according to their BW.The growth level,migration degree of growth trajectory and the incidence of short stature,low weight,overweight and obesity were compared among different BW groups. Results 1) Children with higher BW were always at a high growth level.The BW≥4.00 kg group was 3-4 cm higher and 1.5-2.5 kg heavier than BW<3.00 kg group,and the difference was significant (P<0.001).2) There was a neutralization phenomenon on children′s growth trajectory. The height and weight of different BW groups had a large gap in early infancy,and the gap gradually decreased with age. But the degree of migration of the growth trajectory in different groups was different. The height and weight of the group with BW of 2.50 kg- migrated upwards with age,with an average increase of 25.8 and 23.8 percentiles. The growth level of the groups with BW of 3.00 kg- and 3.50 kg- changed less. The height and weight of the BW≥4.00 kg group moved downward,with an average decrease of 34.2 and 31.9 percentiles.3) The detection rates of short stature and underweight in lower BW group were higher,the detection rates of short stature in these four groups were 4.0%,1.8%,1.0%,0.4%,and the underweight rates were 4.9%,2.0%,0.6% and 0.45%.The overweight rates in four groups were 6.0%,10.5%,16.4%,25.7%,obesity rates were 0.9%,1.9%,4.0%,8.3%,respectively,and there were significant differences among the four groups(P<0.001). Conclusion Children with higher BW are always at a high growth level,and the growth trajectory also have a neutralization phenomenon to some extent.However,children with BW higher than 4.0 kg or lower than 3.0 kg should be paid more attention in order to prevent incidence of short stature,wasting,overweight and obesity.
    Effect of caregivers′ feeding behavior and preschooler′s eating behavior on children′s weight
    YUAN Jing, ZHANG Hao, XU Tong, YANG Xian-jun, YU Li-li, JIANG Xun, SHANG Lei
    2020, 28(6):  627-632.  DOI: 10.11852/zgetbjzz2019-1182
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    Objective To explore the comprehensive effects of caregivers′ feeding behavior and children′s eating behavior on children′s body weight,in order to provide reference for the prevention of childhood obesity and the formulation of early intervention measures. Methods A cross-sectional survey on caregivers′ feeding behaviors and preschool children′s eating behaviors was carried out among 912 preschoolers′ caregivers from April to July 2016.The Chinese Preschooler′s Caregiver Feeding Behavior Scale (CPCFBS) and Chinese Preschooler′s Eating Behavior Questionnaire (CPEBQ) were used to assess caregivers′ feeding behaviors and children′s eating behaviors respectively.Multiple linear regression and Logistic regression analysis were performed to analyze the effects of caregiver feeding behavior and children′s eating behavior on children′s BMI and overweight/obesity after controlling demographic characteristics of the family. Results After controlling the demographic characteristics of the family,multiple stepwise regression analysis showed that weight concerns in the feeding behaviors and food response in the eating behavior were positively correlated with BMI(P<0.05).While responsibility feeding in the feeding behavior of the caregivers and external eating in the children′s eating behavior were negatively correlated with BMI(P<0.05).Logistic regression analysis showed that after controlling the demographic characteristics of the family,weight concerns,food responsiveness in the eating behavior and emotional eating were risk factors for overweight/obesity,while behavior restricted feeding and satiety responsiveness,were protectire factors for overweight/obesity(P<0.05). Conclusion Preschool children′s body weight is influenced by diet behavior and feeding behavior.Preschool children′s obesity can be prevented by cultivating healthy caregiver feeding behavior and children′s eating behavior.
    Correlation between bisphenol A exposure and metabolic syndrome in school-age girls
    ZHAO Jin-hua, HONG Fei, LU Sheng-li, ZHOU Feng, XU Ming
    2020, 28(6):  633-636.  DOI: 10.11852/zgetbjzz2019-0421
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    Objective To investigate the correlation between bisphenol A(BPA) exposure and metabolic syndrome in school-age girls. Methods From September 2016 to September 2017,314 primary school students were randomly selectedfrom Chongchuan District,Gangzha District and Tongzhou Districtto collect urine samples and conduct BPA concentration testing.According to the results of BPA detection,the participants were divided into BPA exposure group and BPA non-exposure group.At the same time,the physical condition of the two groups of children,including body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),fasting blood glucose(FBG),fasting insulin(FIS),triglyceride(TG),total cholesterol(TC) and high-density lipoprotein cholesterol(HDL-C),were measured and evaluated.The differences of each indicator between the two groups and the relationship between each metabolic index and BPA exposure were analyzed. Results Among school-age girls,there were 232 girls in the BPA exposure group and 82 girls in the BPA non-exposure group.The detection rate of BPA was 73.89%.The BMI,SBP,FBG,FIS,TG,and TC of the BPA exposure group were higher than those of the BPA non-expoure group(P<0.05).The HDL-C of the BPA exposwre group was lower than that of the BPA non-exposure group(P<0.05).There were 58 girls (49 girls in the BPA exposure group,9 girls in the non-exposure group) who were overweight and obese,and the detection rate of overweight and obesity was 18.47%.The incidence of overweight and obese girls in the BPA exposure and non-exposure groups wassignificantly different(χ2 = 4.14,P<0.05).Eight girls met the criteria for metabolic syndrome,all in the BPA exposure group. Conclusion Bisphenol A exposure is prevalent in school-age girls.Girls exposed to BPA are more likely to be overweight and obese.In children with metabolic syndrome,the indicators were higher in BPA-exposed girls than in BPA-non-exposed girls,suggesting that there is a correlation between BPA exposure and metabolic syndrome in school-age girls,and exposure to BPA may be one of the risk factors for metabolic syndrome.
    Analysis on the morphology and development of Tibetan and Han nationality among 7- to 18-year-old primary and secondary school students in Sichuan Province
    SHI Chun-li, ZHOU Liang, CHEN Jian-yu, CHENG Lian, ZHANG Li
    2020, 28(6):  637-641.  DOI: 10.11852/zgetbjzz2019-1135
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    Objective To understand the influence of unique climate environment and dietary structure on morphological development in Tibetan areas,so as to provide theoretical basis for the influence of plateau environment and dietary structure on the morphological development of Tibetan primary and secondary school students. Methods Cluster sampling method was used in this survey.A total of 23 469 primary and secondary school students were selected from Tibetan and non-Tibetan areas in Sichuan province in November 2018.The height and weight of the students were measured,and body mass index (BMI) was calculated for analysis of overweight and obesity. Results The average height of Tibetan and Han primary and middle school students were (149.08±16.34)cm and (151.10±15.36)cm,respectively.And the average height of Tibetan students was significantly lower than that of Han students (P<0.05).The average weight of Tibetan and Han primary and middle school students were (44.98±14.40)kg and (45.55±13.57)kg,respectively.And the average weight of Tibetan male students was lower than that of Han students (P<0.05).The detection rate of overweight in Tibetan and Han primary and middle school students were 10.52% and 11.88%,respectively,and it was 6.14% and 7.95% for the detection rate of obesity.The detection rate of overweight and obesity in Tibetan male students were lower than that of Han (P<0.05). Conclusion The average height of Tibetan male primary and secondary school students is lower than that of Han students.The average weight and the detection rate of overweight and obesity of Tibetan primary and secondary school students are lower than that of Han.So it is suggested that Tibetan areas should strengthen nutrition improvement program for primary and secondary school students to ensure that diverse and balanced nutrients are provided,and ensure Tibetan primary and secondary school students grow up healthily.
    Research progress on diet and precocious puberty
    GU Qiu-yun, XIE Lu-yao, SHEN Xiu-hua
    2020, 28(6):  642-644.  DOI: 10.11852/zgetbjzz2019-1086
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    Precocious puberty is defined as the onset of secondary sexual characteristics before the age of 9 in boys and before the age of 8 in girls.Precocious puberty may cause physical and psychological problems in children as well as health issues during adulthood.Recently,the prevalence of precocious puberty has seen a gradually increase.Studies have found that the relationship between diet and precocious puberty is intertwined.Meat,sugary drink,and certain health care products may be risk factors for precocious puberty.However,food with high dietary fiber may be protective factors.Additionally,the relationship between dairy products,beans and their products and precocious puberty is still controversial.The article reviews the research progress on diet and precocious puberty.
    Review on the correlations between parental feeding practices and their preschool children′s eating behaviors
    WANG Jian, ZHU Da-qiao, LI Fang-fang
    2020, 28(6):  645-648.  DOI: 10.11852/zgetbjzz2019-1018
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    Parental feeding practices are closely correlated with their preschool children′s eating behaviors,but the causal relationship between them is not clear yet.The current literature review focuses on the correlations mentioned above,and attempts to analyze the potential reasons for inconsistent findings from relevant studies,so as to provide theoretical basis for further research.
    Progress on global interventions for vitamin A in children
    YANG Fan, LI Ting-yu
    2020, 28(6):  649-652.  DOI: 10.11852/zgetbjzz2019-1116
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    Vitamin A,as one of the most important micronutrients in the body,its deficiency is the leading cause of preventable blindness in children and increases the risk of serious infections leading to disease and death.Vitamin A deficiency remains a major public health problem in most developing countries.Although there are various sources of Vitamin A and ways of supplementation,there is a lack of relatively new policies to guide vitamin A intervention at the national and international levels.Therefore,the following review is made based on the analysis of the latest global Vitamin A deficiency epidemic trend estimation and a large number of intervention studies.
    Vitamin D deficiency and infectious diseases in children
    YANG Xi, LI Yuan-xia, JIA Kun-peng, MA Ke
    2020, 28(6):  653-656.  DOI: 10.11852/zgetbjzz2019-1004
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    Vitamin D is an irreplaceable nutrient for human health.It not only participates in calcium and phosphorus metabolism,maintaining bone health,but also plays an important role in infectious diseases as an immune regulator.Vitamin D also plays an auxiliary role in anti-infection by promoting the production of antimicrobial peptides and affecting immune regulation.This paper reviews Vitamin D deficiency and its association with infectious diseases.
    Possible mechanism of vitamin A deficiency causing anemia in children
    WANG Qin, ZHAO Lin
    2020, 28(6):  657-659.  DOI: 10.11852/zgetbjzz2019-0825
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    Vitamin A(VA) deficiency and anemia in children are worldwide public health problems.Lack of VA will not only cause serious eye diseases in children,but also lead to the occurrence and development of many diseases in children′s respiratory system,immune system,digestive system,blood system,reproductive system and other systems.Anemia also has impact on children′s growth,immune function,learning ability and other aspects.Many studies have confirmed that the deficiency of VA can cause anemia in children,but there is no unified explanation for the specific mechanism.This review summarizes the etiology and mechanism of anemia caused by VA in children.
    Effects of human milk oligosaccharides on infant immunity
    PAN Wei-wei, LI Zai-ling
    2020, 28(6):  660-663.  DOI: 10.11852/zgetbjzz2019-1062
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    Human lactooligosaccharides(HMOs) are a kind of complex sugars linked by monosaccharides through glycoside bonds,which contribute to the development of infant immune system.A small part of HMOs is absorbed into the systemic circulation,most of which reach the colon.Except for the surface of intestinal cavity and intestinal mucosa,HMOs can exert immune function in many parts of the body.This article reviews the interaction between HMOs and intestinal flora in infancy,mediation of immunoregulation,and inhibition of pathogen as well as allergic reaction.
    A case-control study of sleep,diet and behavioral problems in short stature children
    XU Lu, XIAO Yan-feng, WANG Ya-ping, HUANG Jun-peng
    2020, 28(6):  664-667.  DOI: 10.11852/zgetbjzz2019-0951
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    Objective To investigate the sleep,diet and behavioral problems of short stature children, in order to provide scientific basis for early preventing and intervention of short stature. Methods From September 2017 to September 2018,110 cases of short stature children and 110 cases of normal control group were selected from the pediatric outpatient department of the Second Affiliated Hospital of Xi′an Jiaotong University.Their parents were asked to finish the questionnaire survey. Results There were 62 cases with growth hormone deficiency (56.4%),48 cases with idiopathic short stature (43.60%).There were 49 short boys (44.5%) and 61 short girls (55.5%),with an average age of (7.53±2.26) years.The control group consisted of 49 males (44.5%) and 61 females (55.5%),with an average age of (7.33±2.19) years.There was no difference in age and sex between the two groups(P>0.05), but significant differences were found on birth weight,current height and weight,and parental height(P<0.05).There were significant differences on over-satiety response,slow eating,food preference and emotional eating between two group(P<0.05).Compared with the control group,bedtime habits,sleep latency,sleep duration,sleep anxiety,night wake,abnormal sleep,daytime sleepiness of short stature group were all higher.The score of depression,body complaint,social withdrawal,schizoid and aggression of short stature children aged 4-5 years were higher than the control group.The score of body complaint,hyperactivity,schizoid,aggression and discipline violation of short stature group aged 6-11 years old were higher than the control group. Conclusion Diet,sleep and behavioral problems are closely related to children′s growth and development,and are important factors affecting short stature.
    Effects of classroom lighting environment improvement on vision of fourth-grade pupils
    TAO Ran, YANG Zhao-geng, WEN Bo, LI Yan-hui, DONG Bin, MA Jun
    2020, 28(6):  668-671.  DOI: 10.11852/zgetbjzz2019-0904
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    Objective To analyze the effect of the improvement of classroom lighting environment on vision of elementary school students,so as to improve the eyesight health and control poor eyesight among children and adolescents. Methods In March 2017,a total of 291 students from 12 classes of grade 4 of a primary school in Beijing were selected by cluster random sampling,and the standard logarithmic visual acuity chart (5 m) was used to detect the visual acuity of students.6 intervention and 6 control classes were selected.The lights of the intervention classrooms were transformed,and the lights of the control classrooms were unchanged.The effects of different lighting conditions on students′ vision were analyzed by t tests and χ2 tests. Results After the transformation of classroom lighting,the illumination of the desks and blackboard had been improved(301.79 lx vs. 547 lx; 329.89 lx vs 603.18 lx),and the differences were statistically significant(P<0.001).The visual acuity of students decreased after 4 months,but students in the improved the lighting environment had less visual loss (-0.02±0.15 vs. -0.06±0.18,t=-2.122,P=0.035),and fewer students′ eyesight was getting worse(13.29% vs. 22.30%,χ2=4.023,P=0.045). Conclusion Changes in classroom lighting can affect fourth-graders′ vision and the improvement of the classroom light environment can delay the decline of students′ poor vision.
    Correlation between mir-29c and Thl/Th2 cell balance in peripheral blood mononuclear cells of children with allergic asthma
    DONG Tian-jin, TAN Hua-qing, XIU Qing-yong
    2020, 28(6):  672-675.  DOI: 10.11852/zgetbjzz2019-0901
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    Objective To analyze the expression of microRNA 29c (mir-29c) in peripheral blood mononuclear cells of children with allergic asthma (AA) and its correlation with the balance of CD4+helper T cell 1/CD4+helper T cell 2 (Th1/Th2).Methods From October 2015 to December 2018,Totally 94 children with AA were divided into stable group (32 cases),mild acute attack group (27 cases) and moderate acute attack group (35 cases),and another 40 healthy children underwent physical examination were selected as the control group.Peripheral blood was collected from all subjects,serum and peripheral blood mononuclear cell (PBMC) were separated,the levels of mir-29c,Th1/Th2,IFN-gamma,IL-4,T-box transcription factor (T-bet) and GATA binding protein 3 (GATA3) were detected.Results Compared with the control group,the levels of mir-29c,Th2 subgroup,GATA3 protein in PBMC and the level of IL-4 in serum of children with AA in stable group,mild and moderate acute attack group increased in turn,while the percentage of Th1 subgroup,Th1/Th2,T-bet protein level,T-bet/GATA3,serum IFN-γ level and IFN-γ/IL-4 in PBMC decreased in turn,and there was significant difference between any two groups (P<0.05).The levels of mir-29c in peripheral blood of children with AA were negatively correlated with Th1/Th2,IFN-γ/IL-4 and T-bet/GATA3 (r=-0.823,-0.789,-0.804,P<0.05).Conclusion Mir-29c is up-regulated in peripheral blood mononuclear cells of children with AA and may affect the occurrence of AA through Th1/Th2 balance.
    Role of vitamin AD in the rehabilitation of children with exercise retardation
    LYU Nan, MA Cai-yun, LI Jing-jie, SHANG Qing
    2020, 28(6):  676-679.  DOI: 10.11852/zgetbjzz2019-1110
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    Objective To analyze the role of vitamin AD in rehabilitation treatment of children with motor retardation,to guide the clinicl diagnesis. Methods Totally 90 children with motor retardation were randomly divided into control group(n=30), VD group(n=30) and VAD group(n=30).Vitamin A,25 hydroxyvitamin D and IgA levels were detected before and 3 months after treatment,Infection status during hospitalization was investigated. Peabody Motor Development Rating Scale was used to evaluate gross and fine motor ability, and Gessel(Gesell) Development Scale was used to evaluate single development quotient. Results Before treatment, vitamin A and 25-(OH)D levels were lower in the three groups.After 3 months of treatment, the levels of vitamin A and 25-(OH)D in the control group were lower than those before treatment, while those in the VD group were lower and 25-(OH)D levels were higher than those before treatment.Vitamin A and 25-(OH)D levels were increased in VAD group.During hospitalization, the total infection rate was 50% in control group,33.3% in VD group and 13.3% in VAD group.The scores of gross and fine motor function and the evaluation of Gesell Development Scale were improved in the three groups after treatment.The score of gross and fine motor function and the evaluation of VAD group were significantly better than those of VD group and control group.Conclusion Vitamin AD can enhance the resistance, reduce nosocomial infection and improve the curative effect of rehabilitation in children with motor retardation.
    Analysis of physical growth and nutritional status of children and adolescents aged 7 to 18 years in Baoji city
    MU Ya-ning, LIU Ke-li, TANG Shu-bin, ZHOU Jing, XIAO Yan-feng, MA Yong-mei, YONG Cai-xia, ZHANG Shi-jia, REN Xiao-hong
    2020, 28(6):  680-683.  DOI: 10.11852/zgetbjzz2019-1085
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    Objective To evaluate the physical growth and nutritional status of children and adolescents aged 7 to 18 years in Baoji, in order to provide scientific basis for improving growth and development as well as nutrition status of children and adolescents. Methods Totally 27 114 children and adolescents aged 7 to 18 years were randomly selected from Baoji city.Height and weight were measured, and body mass index(BMI) was calculated.The nutritional situation was assessed on the basis of the criteria developed by the data of the nine provinces/municipalities in 2009. Results Except for 10 to 12 years old, the height of boys was higher than that of girls in other age groups(P<0.05). The weight of boys was higher than that of girls at all age groups(P<0.05). Except for 15-and 16-years old,the BMI of boys was higher than that of girls in other age groups(P<0.05).The height of boys more than 14 years old and girls more than 12 years old were significantly higher than those of the whole country, but the national level was higher before the age of 10(P<0.05).The weight of boys more than 10 years old and girls of all ages were higher than those of the whole country(P<0.05).The BMI of boys and girls in all age groups were higher than those of the national level(P<0.05).The detection rates of stunting,underweight, wasting,overweight and obesity were 2.6%,1.5%,9.1%,13.7% and 8.5%,respectively.And the prevalence of boys were higher than those of girls(P<0.05).There were significant differences on the prevalence of stunting,underweight,wasting and obesity among different school age groups(P<0.001). Conclusion There is a double burden of nutrition among children and adolescents in Baoji city, and the rate of overweight/obesity is 1.6 times higher than that of malnutrition,which should be given targeted prevention and control.
    Retrospective analysis of catch-up growth in 247 premature infants
    ZHANG Ying-ying, LI Jing, SHENG Wang-tao, HU Rui, HUANG Ping
    2020, 28(6):  684-688.  DOI: 10.11852/zgetbjzz2019-1061
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    Objective To explore the influencing factors of physical catch-up growth of premature infants,in order to provide a reference for the subdivision intervention stage of catch-up growth of premature infants and the development of personalized follow-up program. Methods A total of 247 preterm infants admitted to Shanghai Children′s Medical Center from October 2010 to September 2016 and followed up regularly after discharge to the corrected age of 1 year,were evaluated for assessing differences on physical development of preterm infants to analyze the related factors of catch-up growth failed by 1 year old of adjusted age. Results Among 247 preterm infants,206(83.4%) cases got catch-up growth before one year old.Multivariate Logistic regression analysis indicated that extrauterine growth restriction(EUGR) with weight evaluation at discharge (OR=4.586,95%CI:1.712-12.288,P=0.002) was the major risk factor for failing in catch-up growth in preterm infants at the corrected age of one year.High-risk of nutritional risk(OR=4.815,95%CI:1.860-12.467,P<0.001),hypertensive diseases of the mother during pregnancy(OR=2.861,95%CI:1.384-5.914,P=0.005) were risk factors for EUGR with weight evaluation, High birth weight (OR=0.151,95%CI:0.065-0.348,P<0.001) was the protective factor for EUGR with weight evaluation.Moreover, the smaller the birth weight was when the gestational age was lower than 32 weeks,the later preterm infant catches up growth would be.The smaller the gestation age,the head circumference of preterm infant reaches the target more slowly. Conclusion Strengthening the management of premature infants in hospital,especially to giving aggressive and reasonable nutritional support strategies for premature infants,reducing the incidence of EUGR and adhering to regular follow-up guidance can help decrease the occurrence of failed catch-up growth in infants.
    Influence of different delivery status on preschool children′s physical fitness
    FENG Pei, HAN Xia, CHEN Lei, LU Ping, WU Bing, XIA Zhi-ying, YU Qian
    2020, 28(6):  689-691.  DOI: 10.11852/zgetbjzz2019-1298
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    Objective To analyze the influence of different delivery status on preschool children′s physical fitness. Methods A total of 3 240 preschool children aged 3 to 6 years in Kunshan city were enrolled in this study through cluster sampling method.Children were surveyed about physical fitness and their delivery status.Multiple linear regression was used to analyze the influence of different delivery status on preschool children′s physical fitness. Results The average score of 3 240 preschool children′s physical fitness was 25.28±4.63.The average score of the boys′ physical fitness (24.44±4.64) was lower than that of the girls′ (26.16±4.45) (t=-10.78,P<0.001).The average physical fitness score of preschool children in low grade (24.25±4.64) was lower than that of the preschool children in middle(25.38±4.54) or high grade (26.04±4.55) (F=40.52,P<0.001).Multiple linear regressions found that the influence of cesarean and dystocia on the preschool children′s physical fitness was not significant after adjustment for gender,grade level (P=0.281).However,prematurity could reduce the average score of preschool children′s physical fitness by 1.08 points after adjustment for gender,grade level(P<0.001),while post maturity had no significant influence on the average score of physical fitness(P=0.678). Conclusion Prematurity could have impact on preschool school children′s physical fitness.
    Effect of breast-feeding quality improvement on breastfeeding rate of very low and extremely low birth weight infants
    JING Lian-fang, LI Yan, WEI Qiu-fen, TAN Wei, YAO Li-ping, MO Yan
    2020, 28(6):  692-695.  DOI: 10.11852/zgetbjzz2019-0773
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    Objective To explore the effect of breast-feeding quality improvement measures on the breastfeeding rate of very low birth weight(VLBW) and extremely low birth weight infants(ELBW) infants,so as to provide basis for clinical application. Methods The clinical data of 258 VLBW and ELBW infants admitted to the hospital from May 2016 to December 2017 were retrospectively analyzed According to whether breastfeeding quality improvement measures were implemented,infants were divided into control group(n=100) and improvement group(n=158). The control group received routine breastfeeding,and the improvement group adopted breastfeeding quality improvement measures.The breast-feeding status,maternal breast-feeding rate during hospitalization,feeding quantity,growth index during hospitalization and incidence of total complications were compared between the two groups. Results The first breast-feeding time,the onset time of adding breast milk fortifier,the time for reaching total intestinal feeding and intravenous nutrition in the improvement group were significantly shorter than those in the control group(P<0.05),the maternal breast-feeding rate and the feeding quantity were significantly higher than those growth of the control group,and the weight,length and head circumference of the patients during hospitalization were significantly higher than those of the control group (P<0.05).The incidence of feeding intolerance and total complications in the improvement group were significantly lower than those in the control group(P< 0.05). Conclusion Breast-feeding quality improvement can significantly improve the breast-feeding situation of VLBW and ELBW infants,increase breast-feeding rate and volume,promote the growth of children,and reduce complications.
    Analysis of serum vitamin E levels of healthy children in china
    XIE Rong, LI Shao-wei, ZHENG Chun-mei, JIN Chun-hua
    2020, 28(6):  696-698.  DOI: 10.11852/zgetbjzz2019-0716
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    Objective To investigate the serum levels of vitamin E in healthy children in China,in order to provide basis for dietary guidance. Methods Serum vitamin E levels were measured by reverse phase high performance liquid chromatography(RP-HPLC) with fluorescence detection method.Clinical data of healthy children in the research group of "Study on the correlation between vitamin A and E levels and the development of children′s recurrent respiratory tract infections" were collected and analyzed. Results A total of 41 964 healthy children were included.The average level of vitamin E was(9.12±2.96)mg/L, and serum vitamin E level decreased with the increasing of age(P<0.001) .Vitamin E deficiency and insufficiency rates accounted for 21.49%, of which, the deficiency rate was only 3.36%(1 409/41 964), and the insufficiency rate was 18.13%(7 609/41 964).The vitamin E deficiency and insufficiency rates of children were different in different age groups, which were 4.1% and 13.0% in children under 3 years old and 2.5% and 24.0% in children older than 3 years old, respectively(P<0.001).There was significant difference on the serum level of vitamin E between different regions of China.Children in eastern and central areas whose serum vitamin E levels were in normal range was more than that in western and northeastern areas(P<0.001). Conclusion In general, serum vitamin E level of healthy children in China is in good condition.Vitamin E deficiency and insufficiency accounted for 1/4 of children aged 3 years and over, and further researches are warranted for exploring reasons.
    Study on the correlation between vitamin A deficiency and anemia as well as physical growth of children in Mianyang city
    XU Wei, HE Cheng-chuan, SONG Guan
    2020, 28(6):  699-702.  DOI: 10.11852/zgetbjzz2019-1344
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    Objective To investigate the vitamin A (VA),anemia and growth levels of infants and young children in Mianyang,and to analyze the relationship between vitamin A deficiency (VAD) and anemia and growth,so as to provide evidence for prevention and control measures. Methods Totally 1 090 children aged 0 to 3 years in the Department of Child Health of Mianyang Maternal and Child Health Care Hospital were selected from May 2017 to July 2019.VA level and anemia were tested,and height and weight were measured and calculated by WHO reference value Z score and malnutrition rate. Results The average VA level was (0.28±0.07)mg/dl,and the detection rates of suspected subclinical vitamin A deficiency (SVAD) and VAD were 50.1% and 9.60%,respectively.There were no significant differences on the detection rates of VAD and VAD between male and female (P>0.05).The prevalence rates of anemia in VAD group and suspected SVAD group were 26.67% and 18.50%,respectively,which was higher than that in normal group 12.98%(P<0.05).The rates of low body weight,growth retardation and marasmus were 1.10%,3.49% and 0.73%,respectively.There were no differences on low body weight,growth retardation and malnutrition among different VA levels(P>0.05),but the excellent growth rate in VA normal group was significantly higher than that in VAD group and suspected SVAD group(χ2WAZ=9.124,P WAZ=0.003;χ2HAZ=6.014,PHAZ=0.014;χ2WHZ=9.276,PWHZ=0.002). Conclusion Mianyang is an area with mild VA deficiency,but more than half of infants and young children are at risk of VAD.Children with VA deficiency and insufficiency are prone to cause anemia and growth retardation,and it is necessary to actively develop prevention and control measures.
    Cohort study on neuropsychological development in preterm infants under 2 years old
    ZHANG Yong, LI Yan-hui, LIANG Jing, LI Jing, JI Yi-lun, GAO Hong, WANG Zhao-hui
    2020, 28(6):  703-705.  DOI: 10.11852/zgetbjzz2020-0118
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    Objective To explore the neuropsychological development of preterm infants, so as to provide basis for targeted early intervention. Methods A total of 326 premature infants (including 123 high-risk premature infants and 203 low-risk premature infants) who established project management in Children′s Health Center of Xi′an Fourth Hospital from March 2016 to October 2019 were enrolled in this study, and meanwhile 206 full-term infants were randomly selected as control group. The neuropsychological development level was evaluated by Gesell Developmental Scales (GDS) at the corrected age of 6, 12 and 24 months old. The results of the evaluation were analyzed by Chi-square test. Results 1) There were significant differences on the development delay rate of five dimensions in GDS among high-risk preterm infants, low-risk preterm infants and term infants at the corrected age of 6, 12 and 24 months old(χ2=13.247, 26.600, 10.652, 15.587, 12.920, 18.475, 30.471, 19.339, 51.203, 6.999, 11.601, 15.888, 7.506, 13.564, 7.696,P<0.05). 2) There were significant differences on gross motor, fine motor and language development in the same group of children at the corrected age of 6, 12 and 24 months old (χ2=42.287,17.416,16.492,29.209,14.267,19.768, 17.679,39.345,11.448, P<0.05). Conclusion The neuropsychological development of preterm infants, especially in high-risk preterm infants, lags behind that of full-term infants. And there are imbalances in the development dimensions. Correct understanding of the neuropsychological development of premature infants is of great significance for the implementation of early intervention.
    Prevalence of picky eating in 6- to 36-month-old and the perception of caregivers towards nutrients intake and body composition
    XU Min, CUI Lei, ZHOU Jing-jing
    2020, 28(6):  706-709.  DOI: 10.11852/zgetbjzz2019-1013
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    Objective To assess the prevalence of picky eating in 6- to 36-month-old Chinese children, and to explore parents′ perceptions of picky eating and nutrition intake. Methods Totally 689 6- to 36-month-old infants and toddlers were included in this study from January 2018 to January 2019.Questionnaires were used to collect information on family demographic factors, child picky eating behaviors, food group rejection, and parents′ perception of child weight status.Dietary intake data was collected via 24 h recall.Children′s length/height and weight were measured. Results Finally 300 infants and toddlers were picky eater,389 infants and toddlers were non-picky eater.And the prevalence of picky eating was 40.00% among 25- to 36-month-old infants and toddlers.There were significant differences on dietary intakes of nutrients between picky and non-picky eaters, such as vitamin A, vitamin B2, vitamin C and protein(P<0.01).Weight status was underestimated by parents of both picky and non-picky children. Conclusion Picky eating seems to be common among 6- to 36-month-old infants and toddlers in China, which will affect the nutrition intake. Therefore, it is supposed to strengtren the perception of nutrition intake in caregives, thus to correct the inappropriate dietary behaviors.
    Grading management and efficacy evaluation of children asthma complicated with allergic rhinitis in medical alliance model based on general-specialist in medical alliance
    ZHANG Wei, CHEN Chun-juan, CAO Kai-feng, XU Nuo, CHEN Zhong, LI Xiao-long
    2020, 28(6):  710-713.  DOI: 10.11852/zgetbjzz2019-1083
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    Objective To explore the grading management and efficacy evaluation of children asthma complicated with allergic rhinitis under medical alliance model of "combination of general practice with specialties". Methods Totally 220 cases of patients with children asthma complicated with allergic rhinitis who received treatment in Shibei Hospital from January to December 2017 were randomly divided into two groups.All patients were referred to the community health service center for health management after their condition was stable.Control group(n=110) was given the conventional extension management model to provide health education, medication guidance and lifestyle intervention and other services.And the children were referred up in time if the disease was aggravated.Research group(n=110) was given standardized management based on general-specialist in medical alliance including establishing disease management team, standardizing diagnosis and treatment path, improving drug catalog and testing function and hierarchical management.The control of asthma and allergic rhinitis and the recognition and satisfaction of parents between two groups were compared and analyzed. Results After 6-month management, the C-AT score [(24.61±2.62)vs.(20.30±2.97)],level of PEF[(91.32±5.23)% vs.(78.12±4.48)%]in the study group was significantly increased, and the score of allergic rhinitis [(0.93±0.25) vs.(2.04±0.42)] was significantly decreased, which was significantly better than that in the control group(P<0.05).The number of acute asthma attacks[(2.14±0.32) time vs.(2.59±0.37)time], length of hospital stay[(8.76±0.85) d vs.(9.41±1.31)d] and medical expenses[(5 028.71±1 037.30) yuan vs.(6 273.20±1 739.41)yuan] in the study group were significantly reduced, the parents of the children in the study group showed a significant increase in their recognition(93.6% vs.85.5%) and satisfaction with the service(91.8% vs.82.7%)compared with the control group(P<0.05). Conclusion Grading management of children asthma complicated with allergic rhinitis in medical alliance model based on general-specialist in medical alliance helps to optimize the allocation of medical resources, realize the homogenization management of hospitals and communities, and has positive significance for the disease control of children and patients′ satisfaction.
    Physical activity guideline for Chinese preschoolers aged 3-6 years
    Working Group on Physical Activity Guideline for Chinese Preschoolers Aged - Years, GUAN Hong-yan, ZHAO Xing, QU Sha, WU Jian-xin, YANG Yu-feng, GUO Jian-jun, ZHANG Ting, LUO Dong-mei
    2020, 28(6):  714-720.  DOI: 10.11852/zgetbjzz2020-0982
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    Physical activity in preschool period is closely related with the development of bone,cardiopulmonary health,motor,cognition and mental health. Moreover,it will continue to influence their health throughout the course of life. Over the past few years,some developed countries,like Canada and Australia,and World Health Organization have published their physical activity guidelines for children in early childhood. However,there are not yet physical activity guidelines for Chinese preschoolers aged 3-6 years. The Physical Activity Guidelines for Chinese Preschoolers (3-6 years old),hereinafter referred to as the "Guidelines",was jointly developed by Capital Institute of Pediatrics,Beijing Sport University,and China Institute of Sports Science from General Administration of Sport of China under an expert team from sports science,pediatrics and public health. The process of developing the Guidelines follows strict and transparent principle,drawing on the Appraisal of Guidelines for Research and Evaluation (AGREE) Ⅱ instrument,adopting the method of literature materials,and sorting out the relevant guidelines and research evidence of foreign preschool children on the basis of systematically searching,forming the core issues and the draft of the recommendations of the guidelines. After repeated discussions and revisions through five rounds of expert consensus meetings,the Guidelines was finally completed. As the first physical activity guideline for preschoolers in China,the Guidelines comprehensively considers movement behaviors of preschoolers in 24 hours of daily life,including physical activity,sedentary behavior and sleep. On this basis,it raises ten key recommendations in four aspects including the principles of preschool children′s physical activity,physical activity time,types of physical activity,and physical activity monitoring and evaluation. The Guidelines provides recommendations for parents,health care professionals,kindergarten teachers and parents,so as to give professional guidance on scientific and safe physical activities for Chinese preschoolers and meet their developmental needs.